RESEARCH ACTIVITIES

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Bioprospecting

• Microbial repository from less/unexplored ecosystems
• Development of plant extract library
• Development of actinobacterial extract library
• Bioprocess development
• Polyphasic microbial taxonomy

 

Medicinal chemistry

• Isolation and characterization of new chemical entities (NCEs)
• Metabolite profiling and dereplication
• Chemical synthesis
• Bioprocess development
• Structure determination of the purified small molecules by NMR, X-ray crystallography and other biophysical and biochemical characterization

 

Bioactivity

• Anti TB screening
• Anti-viral (HIV, HSV, HBV and Dengue) screening
• Anti-cancer assay
• Cytotoxicity testing

 

Proteomics and genomics

• Molecular cloning and recombinant DNA technology
• Phylogenetic analysis
• Drug target identification
• Peptide and Protein engineering
• Infectious diseases diagnostics development
• Computer aided drug design (CADD)